Faecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection (CDI). Now, a multicentre study aimed to investigate whether FMT could be used as treatment in severe and/or complicated cases of CDI. The researchers found that FMT was safe and effective in this patient population (n = 17 total; mean follow-up 11.4 months). Primary and secondary cure rates were 88.2% and 94.1%, respectively, and no adverse effects directly related to FMT were observed.
References
Aroniadis, O. et al. Long-term follow-up study of fecal microbiota transplantation for severe and/or complicated Clostridium difficile infection: a multicenter experience. J. Clin. Gastroenterol. 10.1097/MCG.0000000000000374
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FMT effective in patients with severe and/or complicated CDI. Nat Rev Gastroenterol Hepatol 12, 428 (2015). https://doi.org/10.1038/nrgastro.2015.123
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DOI: https://doi.org/10.1038/nrgastro.2015.123
