Failure to control acute variceal bleeding is a strong predictor of mortality in patients with cirrhosis. Various criteria have been proposed to define failure to control bleeding for use as end points in randomized clinical trials. However, the clinical applicability and validation of these proposed criteria remain unresolved issues.
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The authors declare no competing financial interests.
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Hernández-Gea, V., García-Pagan, J. Can we identify failure to control acute variceal bleeding?. Nat Rev Gastroenterol Hepatol 11, 705–706 (2014). https://doi.org/10.1038/nrgastro.2014.178