New data from a large cohort study describe an increased risk of intrahepatic cholestasis of pregnancy (ICP) in women with prior hepatobiliary disease and confirm the association between ICP and subsequent disease. These findings should prompt a change in clinical practice for guidelines to recommend hepatitis C screening for women with ICP.
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Acknowledgements
C. Williamson has a Wellcome Trust programme grant and project grants from British Liver Trust and SPARKS charity to study gestational metabolic and endocrine disorders, including intrahepatic cholestasis of pregnancy.
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Chappell, L., Williamson, C. Links between hepatobiliary diseases in and beyond pregnancy. Nat Rev Gastroenterol Hepatol 10, 387–388 (2013). https://doi.org/10.1038/nrgastro.2013.92
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DOI: https://doi.org/10.1038/nrgastro.2013.92