In this proof-of-concept study, de Meij et al. have shown that analysis of faecal gas by an electronic nose has potential as a noninvasive screening tool for the detection of advanced neoplasia and colorectal cancer (CRC). The faecal volatile organic compound profiles of patients with CRC or advanced neoplasia could be differentiated from those of controls by the electronic nose—with a sensitivity and specificity of 85% and 87% for CRC, and 62% and 86% for advanced neoplasia.
ORIGINAL RESEARCH PAPER
de Meij, T. G. et al. Electronic nose can discriminate colorectal cancer and advanced adenomas by fecal volatile biomarker analysis: proof of principle study. Int. j. Cancer doi:10.1002/ijc.28446
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Electronic nose can sniff out colorectal cancer and advanced adenomas. Nat Rev Gastroenterol Hepatol 10, 564 (2013). https://doi.org/10.1038/nrgastro.2013.192
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DOI: https://doi.org/10.1038/nrgastro.2013.192