Schistosomiasis mansoni infection is associated with reduced liver function and increased liver fibrosis

Infection with the parasite Schistosomiasis mansoni can lead to hepatic abnormalities, periportal fibrosis and, in severe cases, hepatosplenic schistosomiasis. Blood test results from 55 patients with hepatosplenic schistosomiasis has confirmed that abnormal blood coagulation and liver function tests (including increased levels of serum aminotransferases and reduced levels of albumin when compared with healthy individuals) are associated with periportal fibrosis.