According to new findings from 237 liver transplant recipients and 255 liver donors, liver transplant recipients who carry PNPLA3 rs738409-G are at increased risk of hepatic triglyceride accumulation and steatosis at 1 year and 5 years after transplantation than those with the rs738409-CC genotype. Of note, this increased risk was independent of the graft PNPLA3 genotype.
ORIGINAL RESEARCH PAPER
Finkenstedt, A. et al. PNPLA3 rs738409-G in recipients of liver transplants is a risk factor for graft steatosis. Clin. Gastroenterol. Hepatol. doi:10.1016/j.cgh.2013.06.025
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New risk allele for graft steatosis after liver transplantation. Nat Rev Gastroenterol Hepatol 10, 502 (2013). https://doi.org/10.1038/nrgastro.2013.154
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DOI: https://doi.org/10.1038/nrgastro.2013.154
