Women worry that their IBD will flare during pregnancy. A prospective multicentre study from Europe has now demonstrated that although women with Crohn's disease do not have an increased risk of relapse during pregnancy, women with ulcerative colitis are at increased risk of relapse, both during pregnancy and postpartum.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Selinger, C. P. et al. Inflammatory bowel disease and pregnancy: lack of knowledge is associated with negative views. J. Crohns Colitis 7, e206–e213 (2013).
Pedersen, N. et al. The course of inflammatory bowel disease during pregnancy and postpartum: a prospective European ECCO-EpiCom study of 209 pregnant women. Aliment. Pharmacol. Ther. http://dx.doi.org/10.1111/apt.12412.
Yamamoto, T. Nutrition and diet in inflammatory bowel disease. Curr. Opin. Gastroenterol. 29, 216–221 (2013).
Nielsen, O. H. et al. Pregnancy in ulcerative colitis. Scand. J. Gastroenterol. 18, 735–742 (1983).
Dominitz, J. A. et al. Outcomes in infants born to mothers with inflammatory bowel disease: a population-based cohort study. Am. J. Gastroenterol. 97, 641–648 (2002).
Sykes, L. et al. Changes in the Th1:Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-Δ(12,14)-prostaglandin J2. Mediator. Inflamm. 2012, 416739 (2012).
Mahadevan, U. et al. Intentional infliximab use during pregnancy for induction or maintenance of remission in Crohn's disease. Aliment. Pharmacol. Ther. 21, 733–738 (2005).
Coelho, J. et al. Pregnancy outcome in patients with inflammatory bowel disease treated with thiopurines: cohort from the CESAME study. Gut 60, 198–203 (2011).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Kane, S. Activity of IBD during pregnancy. Nat Rev Gastroenterol Hepatol 10, 571–572 (2013). https://doi.org/10.1038/nrgastro.2013.152
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrgastro.2013.152