Genetic testing in relatives of individuals with Lynch syndrome is of utmost importance for targeted screening and prevention. A recent systematic review suggests that the uptake of testing in at-risk relatives is inadequate and therefore the cost-effectiveness of Lynch syndrome testing is questionable. The results of this study are discussed here.
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Jasperson, K. Cascade genetic testing in Lynch syndrome: room for improvement. Nat Rev Gastroenterol Hepatol 10, 506–508 (2013). https://doi.org/10.1038/nrgastro.2013.122
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DOI: https://doi.org/10.1038/nrgastro.2013.122
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