Huang et al. have shown that breast cancer anti-oestrogen resistance 1 (BCAR1) expression levels are significantly higher in oesophageal squamous cell carcinoma than adjacent normal tissue and are linked to tumour differentiation. High BCAR1 expression levels correlated with reduced survival times and BCAR1 expression levels were a significant and independent prognostic indicator. Elevated BCAR1 expression levels were associated with increased VEGF and p53 expression levels.
ORIGINAL RESEARCH PAPER
Huang, W. et al. Expression of breast cancer anti-estrogen resistance 1 in relation to vascular endothelial growth factor, p53, and prognosis in esophageal squamous cell cancer. Dis. Esophagus doi:10.1111/j.1442-2050.2012.01376.x
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Potential prognostic marker and therapeutic target for oesophageal squamous cell carcinoma?. Nat Rev Gastroenterol Hepatol 9, 488 (2012). https://doi.org/10.1038/nrgastro.2012.147
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DOI: https://doi.org/10.1038/nrgastro.2012.147
