A recent position paper by the American Gastroenterological Association has made a range of excellent recommendations for the management of patients with Barrett esophagus. However, the guidelines have several important limitations, including the omission of endoscopic therapy for patients who have T1 Barrett adenocarcinoma.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Spechler, S. J. et al. American Gastroenterological Association medical position statement on the management of Barrett's esophagus. Gastroenterology 140, 1084–1091 (2011).
Ell, C. et al. Endoscopic mucosal resection of early cancer and high-grade dysplasia in Barrett's esophagus. Gastroenterology 118, 670–677 (2000).
Pech, O. et al. Long-term results and risk factor analysis for recurrence after curative endoscopic therapy in 349 patients with high-grade intraepithelial neoplasia and mucosal adenocarcinoma in Barrett's oesophagus. Gut 57, 1200–1206 (2008).
Pouw, R. E. et al. Properties of the neosquamous epithelium after radiofrequency ablation of Barrett's esophagus containing neoplasia. Am. J. Gastroenterol. 104, 1366–1373 (2009).
Stefanidis, D. et al. Guidelines for surgical treatment of gastroesophageal reflux disease. Surg. Endosc. 24, 2647–2669 (2010).
Moss, A. et al. Endoscopic resection for Barrett's high-grade dysplasia and early esophageal adenocarcinoma: an essential staging procedure with long-term therapeutic benefit. Am. J. Gastroenterol. 105, 1276–1283 (2010).
Konda, V. J. et al. Is the risk of concomitant invasive esophageal cancer in high-grade dysplasia in Barrett's esophagus overestimated? Clin. Gastroenterol. Hepatol. 6, 159–164 (2008.
Oh, D. S. et al. Clinical biology and surgical therapy of intramucosal adenocarcinoma of the esophagus. J. Am. Coll. Surg. 203, 152–161 (2006.
Stein, H. J. et al. Early esophageal cancer: pattern of lymphatic spread and prognostic factors for long-term survival after surgical resection. Ann. Surg. 242, 566–573 (2005).
Pech, O. et al. Comparison between endoscopic and surgical resection of mucosal esophageal adenocarcinoma in Barrett's esophagus at two high-volume centers. Ann. Surg. doi:10.1097/SLA.0b013e31821d4bf6.
Manner H. et al. Final results of a prospective randomized trial on thermal ablation of Barrett's mucosa with concomitant esomeprazole treatment versus surveillance plus PPI in patients cured from early Barrett's cancer by endoscopic resection (APE Study) [abstract]. Gastrointest. Endosc. 78 (Suppl. 1), AB197 (2011).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Behrens, A., Pech, O. Treatment without histology—a dangerous affair. Nat Rev Gastroenterol Hepatol 8, 364–366 (2011). https://doi.org/10.1038/nrgastro.2011.98
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrgastro.2011.98
