Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Endoscopy

Can computer-aided personalized sedation bridge troubled waters?

Subjects

The issue of propofol administration by nonanesthesiologists for upper endoscopy and colonoscopy remains controversial. A recent study investigated the efficacy and safety of a novel computer-assisted personalized sedation device. Patients sedated using the device experienced fewer serious cardiorespiratory events than patients undergoing standard sedation by bolus administration using a hand-held syringe.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Sebel, P. S. & Lowdon, J. D. Propofol: a new intravenous anesthetic. Anesthesiology 71, 260–277 (1989).

    Article  CAS  PubMed Central  Google Scholar 

  2. Roseveare, C. et al. Patient-controlled sedation and analgesia, using propofol and alfentanil, during colonoscopy: a prospective randomized controlled trial. Endoscopy 30, 768–773 (1998).

    Article  CAS  PubMed Central  Google Scholar 

  3. Heuss, L. T. et al. Patient-controlled versus nurse-administered sedation with propofol during colonoscopy. A prospective randomized trial. Am. J. Gastroenterol. 99, 511–518 (2004).

    Article  PubMed Central  Google Scholar 

  4. Doufas, A. G. et al. Automated responsiveness monitor to titrate propofol sedation. Anesth. Analg. 109, 778–786 (2009).

    Article  PubMed Central  Google Scholar 

  5. Pambianco, D. J., Vargo, J. J., Pruitt, R. E., Hardi, R. & Martin, J. F. Computer-assisted personalized sedation for upper endoscopy and colonoscopy: a comparative, multicenter randomized study. Gastrointest. Endosc. doi:10.1016/j.gie.2010.10.031.

    Article  PubMed Central  Google Scholar 

  6. [No authors listed] Practice guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology 96, 1004–1017 (2002).

  7. Rex, D. K. et al. Endoscopist-directed administration of propofol: a worldwide safety experience. Gastroenterology 137, 1229–1237 (2009).

    Article  PubMed Central  Google Scholar 

  8. Vargo, J. J., Cohen, L. B., Rex, D. K. & Kwo, P. Y. Position Statement: Nonanesthesiologist administration of propofol for GI endoscopy. Am. J. Gastroenterol. 104, 2886–2892 (2009).

    Article  PubMed Central  Google Scholar 

  9. Centers for Medicaid and Medicaid Services. Revised Hospital Anesthesia Services Interpretive Guidelines. Centers for Medicare and Medicaid Services [online], (2009).

Download references

Author information

Authors and Affiliations

Authors

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cohen, L. Can computer-aided personalized sedation bridge troubled waters?. Nat Rev Gastroenterol Hepatol 8, 183–184 (2011). https://doi.org/10.1038/nrgastro.2011.31

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrgastro.2011.31

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing