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Nonalcoholic fatty liver disease

Targeted therapy in children—what is the right way?

Nature Reviews Gastroenterology & Hepatology volume 8, pages 425–426 (2011)Cite this article

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The incidence of nonalcoholic fatty liver disease (NAFLD) in children is growing in parallel with that of obesity; however, to date, no drugs have been approved for its treatment. Results from a 5-year clinical trial show that neither metformin nor vitamin E are effective for the treatment of pediatric NAFLD.

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Acknowledgements

The authors wish to thank B. Dallapiccola for his editorial assistance.

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Authors and Affiliations

  1. Autoimmunity and Metabolic Liver Diseases, Liver Research Unit, Bambino Gesù Children's Hospital and Research Institute, S. Onofrio 4 Square, Rome, 00165, Italy

    Anna Alisi & Valerio Nobili

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  1. Anna Alisi
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  2. Valerio Nobili
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Correspondence to Valerio Nobili.

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The authors declare no competing financial interests.

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Alisi, A., Nobili, V. Targeted therapy in children—what is the right way?. Nat Rev Gastroenterol Hepatol 8, 425–426 (2011). https://doi.org/10.1038/nrgastro.2011.117

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