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GERD

Is laparoscopic surgery cost-effective?

A Markov model using data from a randomized, controlled trial has demonstrated that laparoscopic fundoplication is a cost-effective intervention for the management of chronic GERD. However, there are some limitations of the model, discussed below, which suggest that the results should be viewed cautiously until longer follow-up is reported.

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References

  1. Epstein, D., Bojke, L., Sculpher, M. J. & The REFLUX trial group. Laproscopic fundoplication compared with medical management for gastro-oesophageal reflux disease: cost-effectiveness study. BMJ 339, b2576 (2009).

    Article  Google Scholar 

  2. Grant, A. M. et al. Minimal access surgery compared with medical management of chronic gastro-oesophageal reflux disease: UK collaborative randomised trial. BMJ 337, a2664 (2008).

    Article  Google Scholar 

  3. Kaltenbach, T., Crockett, S. & Gerson, L. B. Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach. Arch. Intern. Med. 166, 965–971 (2006).

    Article  Google Scholar 

  4. Khan, M., Santana, J., Donnellan, C., Preston, C. & Moayyedi, P. Medical treatments in the short term management of reflux oesophagitis. Cochrane Database of Systematic Reviews, Issue 2. Art. No.: CD003244. doi:10.1002/14651858.CD003244.pub2 (2007).

    Google Scholar 

  5. Donnellan, C., Sharma, N., Preston, C. & Moayyedi, P. Medical treatments for the maintenance therapy of reflux oesophagitis and endoscopic negative reflux disease. Cochrane Database of Systematic Reviews, Issue 1. Art. No.: CD003245. doi:10.1002/14651858.CD003245.pub2 (2005).

    Google Scholar 

  6. Laheij, R. J. et al. Risk of community-acquired pneumonia and use of gastric acid-suppressive drugs. JAMA 292, 1955–1960 (2004).

    Article  CAS  Google Scholar 

  7. Yang, Y. X., Lewis, J. D., Epstein, S. & Metz, D. C. Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA 296, 2947–2953 (2006).

    Article  CAS  Google Scholar 

  8. Ho, P. M. et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA 301, 937–944 (2009).

    Article  CAS  Google Scholar 

  9. National Health Service. The October 2009 Electronic Drug Tariff. National Health Service [online], (2009).

Download references

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Correspondence to Alexander C. Ford.

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Ford, A. Is laparoscopic surgery cost-effective?. Nat Rev Gastroenterol Hepatol 6, 695–696 (2009). https://doi.org/10.1038/nrgastro.2009.196

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