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Reproductive endocrinology

Are intramuscular testosterone injections harmful?

Nature Reviews Endocrinology volume 11, pages 510–511 (2015)Cite this article

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Injectable testosterone esters and transdermal testosterone gels have generally been assumed to be equally safe and effective forms of testosterone-replacement therapy for male hypogonadism. Now, findings from a recent study suggest that transdermal testosterone gels are superior to injectable testosterone esters in terms of reducing cardiovascular events, all-cause hospitalizations and all-cause mortality.

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Acknowledgements

The authors acknowledge J. K. Amory and S. T. Page for reviewing the manuscript and skilful critiques.

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Authors and Affiliations

  1. Department of Medicine, University of Washington, Box 356420, 1959 NE Pacific Street, Seattle, 98195, WA, USA

    Bradley D. Anawalt & William J. Bremner

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  1. Bradley D. Anawalt
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  2. William J. Bremner
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Correspondence to William J. Bremner.

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The authors declare no competing financial interests.

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Anawalt, B., Bremner, W. Are intramuscular testosterone injections harmful?. Nat Rev Endocrinol 11, 510–511 (2015). https://doi.org/10.1038/nrendo.2015.111

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