A new cohort study links work-related stress to an increased risk of developing type 2 diabetes mellitus (T2DM) in women, but the findings are less clear in men. Randomized controlled studies are now needed to determine whether management of stress could be used to reduce the risk of developing T2DM.
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References
Karasek, R., Baker, D., Marxer, F., Ahlbom, A. & Theorell, T. Job decision latitude, job demands, and cardiovascular disease: a prospective study of Swedish men. Am. J. Public Health 71, 694–705 (1981).
Kivimäki, M. et al. Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data. Lancet 380, 1491–1497 (2012).
Eriksson, A. K., van den Donk, M., Hilding, A. & Östenson, C. G. Work stress, sense of coherence, and risk of type 2 diabetes in a prospective study of middle-aged Swedish men and women. Diabetes Care http://dx.doi.org/10.2337/dc12-1738.
Brunner, E. Biology and health inequality. PLoS Biol. 5, e267 (2007).
Chida, Y. & Steptoe, A. Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis. Biol. Psychol. 80, 265–278 (2009).
Heraclides, A. M., Chandola, T., Witte, D. R. & Brunner, E. J. Work stress, obesity and the risk of type 2 diabetes: gender-specific bidirectional effect in the Whitehall II study. Obesity (Silver Spring) 20, 428–433 (2012).
Knowler, W. C. et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 346, 393–403 (2002).
Steptoe, A. & Kivimäki, M. Stress and cardiovascular disease: an update on current knowledge. Ann. Rev. Public Health 34, 337–354 (2013).
Ioannidis, J. P. et al. Comparison of evidence of treatment effects in randomized and nonrandomized studies. JAMA 286, 821–830 (2001).
Acknowledgements
E. J. Brunner's research is supported by the British Heart Foundation (RG/13/2/30098). M. Kivimäki's work is supported by the Medical Research Council (K013351), the NIH (HL36310 and AG034454) and a professorial fellowship from the Economic and Social Research Council.
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Brunner, E., Kivimäki, M. Work-related stress and the risk of type 2 diabetes mellitus. Nat Rev Endocrinol 9, 449–450 (2013). https://doi.org/10.1038/nrendo.2013.124
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DOI: https://doi.org/10.1038/nrendo.2013.124
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