Insulin resistance has a key role in the pathogenesis of polycystic ovary syndrome, a common endocrinopathy that affects young women. Therefore, the use of insulin-sensitizing agents has been studied extensively in this patient population. Given the effectiveness of metformin and thiazolidinediones in previous studies, the question arises: is one class better than the other?
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Grover, A., Yialamas, M. Metformin or thiazolidinedione therapy in PCOS?. Nat Rev Endocrinol 7, 128–129 (2011). https://doi.org/10.1038/nrendo.2011.16
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DOI: https://doi.org/10.1038/nrendo.2011.16