Cut-off values for the peak growth hormone level after an arginine plus growth hormone releasing hormone (Arg-GHRH) stimulation test for the diagnosis of growth hormone deficiency might require adjustment for young adults with obesity. Abdominal obesity is a stronger predictor of the growth hormone response to Arg-GHRH stimulation than BMI or age, and should be considered in adult patients who are evaluated for growth hormone deficiency.
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Johannsson, G. A reappraisal of the diagnosis of growth hormone deficiency. Nat Rev Endocrinol 6, 190–191 (2010). https://doi.org/10.1038/nrendo.2010.21
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DOI: https://doi.org/10.1038/nrendo.2010.21
