The THERAPY trial investigators conclude that, when pregnancy is confirmed in adequately treated women with hypothyroidism, doubling the dose of prepregnancy levothyroxine on 2 days each week safely prevents maternal hypothyroidism in the first trimester of pregnancy in most cases. Is this really the best strategy to adopt?
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Chan, S. Early adjustment of levothyroxine treatment in pregnancy. Nat Rev Endocrinol 6, 537–538 (2010). https://doi.org/10.1038/nrendo.2010.149
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DOI: https://doi.org/10.1038/nrendo.2010.149
