Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Reproductive endocrinology

Male hormonal contraceptive passes efficacy test in China

Nature Reviews Endocrinology volume 5, pages 359–360 (2009)Cite this article

Traditional methods of male contraception, such as condoms and vasectomy, are unacceptable to many couples as they can be unreliable or the effects not easily reversed. Depot administration of male hormonal contraception could provide a safe, effective, reliable and reversible alternative, report researchers in China.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Gu, Y. Q. et al. Multicenter contraceptive efficacy trial of injectable testosterone undecanoate in Chinese men. J. Clin. Endocrinol. Metab. doi: 10.1210/jc.2008–1846

  2. Aaltonen, P. et al. 10th Summit Meeting consensus: recommendations for regulatory approval for hormonal male contraception. J. Androl. 28, 362–363 (2007).

    Article  Google Scholar 

  3. Li, J. W. & Gu, Y. Q. Predictors for partial suppression of spermatogenesis of hormonal male contraception. Asian J. Androl. 10, 723–730 (2008).

    Article  CAS  Google Scholar 

  4. Gu, Y. Q. et al. A multicenter contraceptive efficacy study of injectable testosterone undecanoate in healthy Chinese men. J. Clin. Endocrinol. Metab. 88, 562–568 (2003).

    Article  CAS  Google Scholar 

  5. [No authors listed] World Health Organization Task Force on methods for the regulation of male fertility. Contraceptive efficacy of testosterone-induced azoospermia in normal men. Lancet 336, 955–959 (1990).

  6. [No authors listed] World Health Organization Task Force on methods for the regulation of male fertility. Contraceptive efficacy of testosterone-induced azoospermia and oligozoospermia in normal men. Fertil. Steril. 65, 821–829 (1996).

  7. Turner, L. et al. Contraceptive efficacy of a depot progestin and androgen combination in men. J. Clin. Endocrinol. Metab. 88, 4659–4667 (2003).

    Article  CAS  Google Scholar 

  8. Trussell, J. Contraceptive failure in the United States. Contraception 70, 89–96 (2004).

    Article  Google Scholar 

  9. Kost, K., Singh, S., Vaughan, B., Trussell, J. & Bankole, A. Estimates of contraceptive failure from the 2002 National Survey of Family Growth. Contraception 77, 10–21 (2008).

    Article  Google Scholar 

  10. Meriggiola, M. C. et al. Norethisterone enanthate plus testosterone undecanoate for male contraception: effects of various injection intervals on spermatogenesis, reproductive hormones, testis, and prostate. J. Clin. Endocrinol. Metab. 90, 2005–2014 (2005).

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. J. K. Amory, Department of Medicine and the Center for Research in Reproduction and Contraception, University of Washington School of Medicine, Campus Box 356429, 1959 NE Pacific Street, Seattle, WA 98195, USA jamory@u.washington.edu

Authors and Affiliations

  1. Department of Medicine and the Center for Research in Reproduction and Contraception, University of Washington School of Medicine, Seattle, WA, USA

    John K. Amory

Authors
  1. John K. Amory
    View author publications

    You can also search for this author in PubMed Google Scholar

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Amory, J. Male hormonal contraceptive passes efficacy test in China. Nat Rev Endocrinol 5, 359–360 (2009). https://doi.org/10.1038/nrendo.2009.110

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrendo.2009.110

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing