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Manipulating the brain with epigenetics

Nature Neuroscience volume 13, pages 405–406 (2010)Cite this article

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A study finds that the DNA methylation enzymes Dnmt1 and Dnmt3a are needed to maintain the epigenetic landscape in nondividing, postmitotic neurons and that this process is required for normal learning and memory.

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Figure 1: DNA methylation and histone acetylation are two critical epigenetic mechanisms controlling chromatin structure and function in postmitotic mammalian neurons.

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  1. The author is in the Department of Psychology, University of California Riverside, Riverside, California, USA.,

    Edward Korzus

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  1. Edward Korzus
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Correspondence to Edward Korzus.

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The author declares no competing financial interests.

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Korzus, E. Manipulating the brain with epigenetics. Nat Neurosci 13, 405–406 (2010). https://doi.org/10.1038/nn0410-405

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