Brief Communication

Cued memory reactivation during sleep influences skill learning

  • Nature Neuroscience volume 15, pages 11141116 (2012)
  • doi:10.1038/nn.3152
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Abstract

Information acquired during waking can be reactivated during sleep, promoting memory stabilization. After people learned to produce two melodies in time with moving visual symbols, we enhanced relative performance by presenting one melody during an afternoon nap. Electrophysiological signs of memory processing during sleep corroborated the notion that appropriate auditory stimulation that does not disrupt sleep can nevertheless bias memory consolidation in relevant brain circuitry.

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Acknowledgements

We thank B. Mander, J. Saletin, S. Greer and D. Oudiette for technical help. This material is based on work supported by National Science Foundation grant BCS1025697, National Institute of Aging grant T32-AG020418 and National Institute of Neurological Diseases and Stroke grant T32-NS047987.

Author information

Affiliations

  1. Interdepartmental Neuroscience Program, Northwestern University, Evanston, Illinois, USA.

    • James W Antony
    • , Eric W Gobel
    • , Paul J Reber
    •  & Ken A Paller
  2. Department of Psychology, Northwestern University, Evanston, Illinois, USA.

    • Justin K O'Hare
    • , Paul J Reber
    •  & Ken A Paller

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Contributions

J.W.A. and K.A.P. conceived the design and all of the authors contributed to developing the procedures. J.W.A. and J.K.O. collected the data. J.W.A. analyzed the data. J.W.A. and K.A.P. wrote the manuscript. All of the authors discussed the results and finalized the manuscript.

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Ken A Paller.

Supplementary information

PDF files

  1. 1.

    Supplementary Text and Figures

    Supplementary Figures 1–5, Supplementary Table 1 and Supplementary Results

Videos

  1. 1.

    Supplementary Movie 1

    A real-time movie of task performance.