A variant gene for antigen presentation is associated with tissue damage in multiple sclerosis. The damaging effects are now shown to be dampened by an allele of a second, neighboring gene.
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Kim Caesar
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Trowsdale, J. Multiple sclerosis: putting two and two together. Nat Med 12, 1119–1121 (2006). https://doi.org/10.1038/nm1006-1119
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DOI: https://doi.org/10.1038/nm1006-1119
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