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Bad Blood: A trigger for TRALI

Nature Medicine volume 16, pages 382–383 (2010)Cite this article

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In the US, approximately 14–15 million units of blood are collected annually and transfused to about 5 million people1. About 1,000 of these recipients will develop transfusion-related acute lung injury (TRALI). A few hours after blood infusion, people who experience this complication suffer from respiratory symptoms with hypoxia, associated with inflammation in the lung or exacerbation of a preexisting pulmonary condition.

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Author information

Authors and Affiliations

  1. Paul S. Frenette is in the Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA.,

    Paul S Frenette

  2. Narla Mohandas is at the New York Blood Center, New York, New York, USA.,

    Narla Mohandas

Authors
  1. Paul S Frenette
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  2. Narla Mohandas
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Corresponding author

Correspondence to Paul S Frenette.

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Competing interests

P.S.F. has served as a consultant for Glycomimetics.

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Frenette, P., Mohandas, N. Bad Blood: A trigger for TRALI. Nat Med 16, 382–383 (2010). https://doi.org/10.1038/nm0410-382

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