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Quantifying the activity of anti-HIV treatment in silico

Nature Medicine volume 18, pages 355–356 (2012)Cite this article

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Combination-based antiretroviral therapy has been very successful in preventing disease progression in HIV-infected individuals. However, a rational method for predicting the effect of a particular drug combination on clinical outcome is needed. A new study takes us closer to this goal by computationally predicting the inhibitory effects of combinations of three antiretroviral drugs (pages 446–451).

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Figure 1: Devising a quantitative model to predict inhibition of HIV-1 infection by combinations of antiretroviral drugs.

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Authors and Affiliations

  1. Ruy M. Ribeiro is in Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, USA.,

    Ruy M Ribeiro

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  1. Ruy M Ribeiro
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Correspondence to Ruy M Ribeiro.

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The author declares no competing financial interests.

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Ribeiro, R. Quantifying the activity of anti-HIV treatment in silico. Nat Med 18, 355–356 (2012). https://doi.org/10.1038/nm.2698

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