Commentary | Published:

A model for harmonizing flow cytometry in clinical trials

Nature Immunology volume 11, pages 975978 (2010) | Download Citation

  • A Corrigendum to this article was published on 15 February 2011

This article has been updated

Complexities in sample handling, instrument setup and data analysis are barriers to the effective use of flow cytometry to monitor immunological parameters in clinical trials. The novel use of a central laboratory may help mitigate these issues.

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Change history

  • 12 November 2010

    In the version of this article initially published, a group of author names and their affiliation in the FOCIS Human Immunophenotyping Consortium was incorrect. The correct names and affiliation are as follows: Paola Di Meglio, Frank O. Nestle, Mark Peakman and Federica Villanova are at King's College London, London, UK. The error has been corrected in the HTML and PDF versions of the article.

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Author information

Affiliations

  1. Holden T. Maecker is with the Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, California, USA.

    • Holden T Maecker
  2. J. Philip McCoy Jr. is with the National Heart, Lung, and Blood Institute, US National Institutes of Health, Bethesda, Maryland, USA.

    • J Philip McCoy Jr
  3. Michael Amos, John Elliott, Adolfas Gaigalas and Lili Wang are with the National Institute of Standards and Technology, Gaithersburg, Maryland, USA.

    • Michael Amos
    • , John Elliott
    • , Adolfas Gaigalas
    •  & Lili Wang
  4. Richard Aranda is with Bristol Myers-Squibb, Princeton, New Jersey, USA.

    • Richard Aranda
  5. Jacques Banchereau is with Baylor Institute for Immunology Research, Dallas, Texas, USA.

    • Jacques Banchereau
  6. Chris Boshoff is with the Foundation for the National Institutes of Health, Bethesda, Maryland, USA.

    • Chris Boshoff
  7. Jonathan Braun, Yael Korin and Elaine Reed are at the University of California, Los Angeles, California, USA.

    • Jonathan Braun
    • , Yael Korin
    •  & Elaine Reed
  8. Judy Cho and David Hafler are at Yale University, New Haven, Connecticut, USA.

    • Judy Cho
    •  & David Hafler
  9. Mark Davis, C. Garrison Fathman and William Robinson are at Stanford University, Stanford, California, USA.

    • Mark Davis
    • , C Garrison Fathman
    •  & William Robinson
  10. Thomas Denny and Kent Weinhold are at Duke University, Durham, North Carolina, USA.

    • Thomas Denny
    •  & Kent Weinhold
  11. Bela Desai is with Schering Plough, Palo Alto, California, USA.

    • Bela Desai
  12. Betty Diamond and Peter Gregersen are with the Feinstein Institute for Medical Research, Manhasset, New York, USA.

    • Betty Diamond
    •  & Peter Gregersen
  13. Paola Di Meglio, Frank O. Nestle, Mark Peakman and Federica Villanova are at King's College London, London, UK.

    • Paola Di Meglio
    • , Frank O Nestle
    • , Mark Peakman
    •  & Federica Villanova
  14. John Ferbas is with Amgen, Thousand Oaks, California, USA.

    • John Ferbas
  15. Elizabeth Field is at the University of Iowa, Iowa City, Iowa, USA.

    • Elizabeth Field
  16. Aaron Kantor is with the Immune Tolerance Institute, Menlo Park, California, USA.

    • Aaron Kantor
  17. Thomas Kawabata is with Pfizer, Groton, Connecticut, USA.

    • Thomas Kawabata
  18. Wendy Komocsar is with Eli Lilly, Indianapolis, Indiana, USA.

    • Wendy Komocsar
  19. Michael Lotze is at the University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

    • Michael Lotze
  20. Jerry Nepom is with the Benaroya Research Institute, Seattle, Washington, USA.

    • Jerry Nepom
  21. Hans Ochs is at the University of Washington, Seattle, Washington, USA.

    • Hans Ochs
  22. Raegan O'Lone is with the International Life Sciences Health and Environmental Sciences Institute, Washington, DC, USA.

    • Raegan O'Lone
  23. Deborah Phippard is with the Immune Tolerance Network, Bethesda, Maryland, USA.

    • Deborah Phippard
  24. Scott Plevy is at the University of North Carolina, Chapel Hill, North Carolina, USA.

    • Scott Plevy
  25. Stephen Rich is at the University of Virginia, Charlottesville, Virginia, USA.

    • Stephen Rich
  26. Mario Roederer and Dan Rotrosen are with the National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.

    • Mario Roederer
    •  & Dan Rotrosen
  27. Jung-Hua Yeh is with Genentech, South San Francisco, California, USA.

    • Jung-Hua Yeh

Consortia

  1. the FOCIS Human Immunophenotyping Consortium

Authors

  1. Search for Holden T Maecker in:

  2. Search for J Philip McCoy in:

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Holden T Maecker.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/ni1110-975

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