Abstract
Potent cytotoxic T lymphocytes are needed for effective tumor eradication. Transfer of genes encoding tumor-specific receptors into T cells allows the efficient generation of an immune response.
*NOTE: It should be noted that the optimal MDM2 cytotoxic epitope was amino acids 81–88, as shown in the figure, rather than amino acids 80–88, as mentioned in the text.
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Moss, P. Redirecting T cell specificity by TCR gene transfer. Nat Immunol 2, 900–901 (2001). https://doi.org/10.1038/ni1001-900
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DOI: https://doi.org/10.1038/ni1001-900
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