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Hematopoiesis flies high with Ikaros

Ikaros regulatory proteins are essential for proper lymphoid cell development. Several new functions for Ikaros have been defined by surrogate marker expression in early hematopoietic progenitor populations.

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Figure 1: Working model of early hematopoietic development.

Katie Ris

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Smale, S., Dorshkind, K. Hematopoiesis flies high with Ikaros. Nat Immunol 7, 367–369 (2006). https://doi.org/10.1038/ni0406-367

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