Maintenance of a memory cell population is thought to be independent of antigen. However, it has now been shown that unless memory cells get some signals via MHC, they become functionally defective.
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Bob Crimi
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Rocha, B. Requirements for memory maintenance. Nat Immunol 3, 209–210 (2002). https://doi.org/10.1038/ni0302-209
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DOI: https://doi.org/10.1038/ni0302-209
