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NK cells join the plasticity party

Nature Immunology volume 18, pages 959960 (2017) | Download Citation

The cytokine TGF-β allows tumors to evade the immune system by converting conventional natural killer cells into type 1 innate lymphoid cells devoid of cytotoxic function.

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Author information

Affiliations

  1. Jonathan S. Silver and Alison A. Humbles are in the Department of Respiratory, Inflammation and Autoimmunity, MedImmune, Gaithersburg, Maryland, USA.

    • Jonathan S Silver
    •  & Alison A Humbles

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Competing interests

J.S.S. and A.A.H. are full-time employees of MedImmune and hold shares in AstraZeneca.

Corresponding author

Correspondence to Alison A Humbles.

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DOI

https://doi.org/10.1038/ni.3817

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