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GPR15: a tale of two species

Nature Immunology volume 16, pages 137139 (2015) | Download Citation

The chemoattractant receptor GPR15 directs the homing of T cells to the colon; however, GRP15 expression differs in the effector and regulatory T cell subsets of humans versus those of mice. These findings have profound implications for the potential targeting of GRP15 for therapeutic intervention.

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Author information

Affiliations

  1. Janine Bilsborough is with the F. Widjaja Foundation Inflammatory Bowel and Immunobiology Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

    • Janine Bilsborough
  2. Joanne L. Viney is with Immunology Research, Biogen Idec, Cambridge, Massachusetts, USA.

    • Joanne L Viney

Authors

  1. Search for Janine Bilsborough in:

  2. Search for Joanne L Viney in:

Competing interests

J.L.V. is employed by Biogen Idec.

Corresponding author

Correspondence to Joanne L Viney.

About this article

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DOI

https://doi.org/10.1038/ni.3084

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