Two recent large-scale sequencing studies have identified multiple genetic aberrations in pediatric low-grade gliomas. These findings offer substantial insights that may spur the development of new diagnostics and treatments for these cancers.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Jones, D.T. et al. Nature 488, 100–105 (2012).
Rausch, T. et al. Cell 148, 59–71 (2012).
Robinson, G. et al. Nature 488, 43–48 (2012).
Wu, G. et al. Nat. Genet. 44, 251–253 (2012).
Schwartzentruber, J. et al. Nature 482, 226–231 (2012).
Pfister, S. et al. J. Clin. Invest. 118, 1739–1749 (2008).
Zhang, J. et al. Nat. Genet. 45, 602–612 (2013).
Jones, D.T.W. et al. Nat. Genet. 45, 927–932 (2013).
Sievert, A.J. et al. Brain Pathol. 19, 449–458 (2009).
Schindler, G. et al. Acta Neuropathol. 121, 397–405 (2011).
Yan, H. et al. N. Engl. J. Med. 360, 765–773 (2009).
Turcan, S. et al. Nature 483, 479–483 (2012).
Liu, X.Y. et al. Acta Neuropathol. 124, 615–625 (2012).
Kannan, K. et al. Oncotarget 3, 1194–1203 (2012).
Jiao, Y. et al. Oncotarget 3, 709–722 (2012).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Turcan, S., Chan, T. MAPping the genomic landscape of low-grade pediatric gliomas. Nat Genet 45, 847–849 (2013). https://doi.org/10.1038/ng.2706
Published:
Issue Date:
DOI: https://doi.org/10.1038/ng.2706
This article is cited by
-
Review of low-grade gliomas in children—evolving molecular era and therapeutic insights
Child's Nervous System (2015)
