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Dose escalation with proton-beam boost for low-risk prostate cancer

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References

  1. Shipley WU et al. (1995) Advanced prostate cancer: the results of a randomized comparative trial of high dose irradiation boosting with conformal protons compared with conventional dose irradiation using photons alone. Int J Radiat Oncol Biol Phys 32: 3–12

    Article  CAS  Google Scholar 

  2. Pollack A et al. (2002) Prostate cancer radiation dose response: results of the M.D. Anderson phase III randomized trial. Int J Radiat Oncol Biol Phys 53: 1097–1105

    Article  Google Scholar 

  3. Valicenti R et al. (2000) Survival advantage from higher-dose radiation therapy for clinically localized prostate cancer treated on the Radiation Therapy Oncology Group trials. J Clin Oncol 18: 2740–2746

    Article  CAS  Google Scholar 

  4. Kuban D et al. (2003) Hazards of dose escalation in prostate cancer radiotherapy. Int J Radiat Oncol Biol Phys 57: 1260–1268

    Article  Google Scholar 

  5. de Crevoisier R et al. (2005) Increased risk of biochemical and local failure in patients with distended rectum on the planning CT for prostate cancer radiotherapy. Int J Radiat Oncol Biol Phys 62: 965–973

    Article  Google Scholar 

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Acknowledgements

The synopsis was written by Petra Roberts, Associate Editor, Nature Clinical Practice.

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Correspondence to Richard K Valicenti.

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The authors declare no competing financial interests.

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Trabulsi, E., Valicenti, R. Dose escalation with proton-beam boost for low-risk prostate cancer. Nat Rev Urol 3, 256–257 (2006). https://doi.org/10.1038/ncpuro0477

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