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Does adjuvant androgen suppression after radiotherapy for prostate cancer improve long-term outcomes?

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References

  1. Pilepich MV et al. (2005) Androgen suppression adjuvant to definitive radiotherapy in prostate carcinoma—long-term results of phase III RTOG 85-31. Int J Radiat Oncol Biol Phys 61: 1285–1290

    Article  CAS  Google Scholar 

  2. Pilepich MV et al. (1997) Phase III trial of androgen suppression using goserelin in unfavorable-prognosis carcinoma of the prostate treated with definitive radiotherapy: report of Radiation Therapy Oncology Group protocol 85-31. J Clin Oncol 15: 1013–1021

    Article  CAS  Google Scholar 

  3. Lawton CA et al. (2001) Updated results of the phase III Radiation Therapy Oncology Group (RTOG) trial 85-31 evaluating the potential benefit of androgen suppression following standard radiation therapy for unfavorable prognosis carcinoma of the prostate. Int J Radiat Oncol Biol Phys 49: 937–946

    Article  CAS  Google Scholar 

  4. Hanks GE et al. (2003) Phase III trial of long-term adjuvant androgen deprivation after neoadjuvant hormonal cytoreduction and radiotherapy in locally advanced carcinoma of the prostate: the Radiation Therapy Oncology Group protocol 92-02. J Clin Oncol 21: 3972–3978

    Article  CAS  Google Scholar 

  5. Pilepich MV et al. (2001) Phase III Radiation Therapy Oncology Group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate. Int J Radiat Oncol Biol Phys 50: 1243–1252

    Article  CAS  Google Scholar 

  6. Bolla M et al. (2002) Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EORTC study): a phase III randomised trial. Lancet 360: 103–106

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Sandra Michelmore, Associate Editor, Nature Clinical Practice.

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Correspondence to Michel Bolla.

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Bolla, M. Does adjuvant androgen suppression after radiotherapy for prostate cancer improve long-term outcomes?. Nat Rev Urol 2, 536–537 (2005). https://doi.org/10.1038/ncpuro0331

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