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Can a noninvasive penile-cuff test predict bladder outlet obstruction?

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References

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Acknowledgements

The synopsis was written by Sandra Michelmore, Associate Editor, Nature Clinical Practice.

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Correspondence to J Christian Winters.

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Glossary

DETRUSOR HYPOCONTRACTILITY (DH)

Detrusor muscle contraction of reduced strength and/or duration leading to incomplete or prolonged bladder emptying in the absence of urethral obstruction

DETRUSOR OVERACTIVITY (DO)

Involuntary detrusor muscle contractions during the filling phase; may be spontaneous or provoked

BLADDER OUTLET OBSTRUCTION (BOO)

Obstruction that reduces or prevents urine flow into the urethra; characterized by increased detrusor pressure and reduced urine flow rate, and most commonly caused by benign prostate enlargement

PRESSURE FLOW STUDY (PFS)

Abdominal, bladder, and detrusor pressures, and flow rate, are simultaneously recorded for quantitative assessment of voiding function

QMAX

Peak urinary flow rate

DETRUSOR PRESSURE (PDET)

The component of bladder pressure caused by forces in the bladder wall, estimated by subtracting the abdominal pressure from the bladder pressure

PDET.ISV

The maximum isovolumetric detrusor pressure obtained during combined PFS/penile-cuff test

ROC (RECEIVER OPERATING CHARACTERISTIC)

A statistical validation tool used to measure how well logistic regression models have predicted a particular binary outcome; the area under the curve equates to the probability of being able to discriminate between the two possible outcomes, with the ideal value being 1.0

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Winters, J. Can a noninvasive penile-cuff test predict bladder outlet obstruction?. Nat Rev Urol 2, 126–127 (2005). https://doi.org/10.1038/ncpuro0123

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