Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Review Article
  • Published:

Nonpharmacologic management of osteoporosis to minimize fracture risk

Abstract

The traditional management of osteoporosis has focused on the pharmacologic aspects of treatment. Nonpharmacologic approaches, such as the use of orthoses, exercise programs, calcium and vitamin D supplementation, fall prevention, and kyphoplasty have largely been overlooked. Evidence for an essential contribution of nonpharmacologic treatments in the management of osteoporotic patients is increasing, particularly for patients who cannot, or will not, comply with medication regimens. This Review highlights the most important aspects of nonpharmacologic management of osteoporosis.

Key Points

  • Osteoporosis is a condition that should be treated using a comprehensive approach, focusing on both pharmacologic and nonpharmacologic treatment

  • Orthoses, such as back braces and hip protectors, can help in the prevention and treatment of fractures

  • Exercise programs, such as tai chi and physical therapy programs, are essential for improving balance and building strength

  • Calcium and vitamin D are critical supplements; vitamin D deficiency has been recognized as an epidemic

  • Fall prevention requires environmental modifications and minimization of potentially hazardous medications

  • Kyphoplasty is a minimally invasive spine procedure that can decrease pain and improve kyphosis in patients with painful vertebral compression fractures

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Orthoses often prescribed for osteoporotic patients.
Figure 2: Sun exposure allows conversion of 7-dehydrocholesterol to previtamin D3 in the skin, which is then quickly converted to vitamin D3 (cholecalciferol).

Similar content being viewed by others

References

  1. Sinaki M et al. (2002) Stronger back muscles reduce the incidence of vertebral fractures: a prospective 10 year follow-up of postmenopausal women. Bone 30: 836–841

    Article  CAS  Google Scholar 

  2. Kaplan RS and Sinaki M (1993) Posture Training Support: preliminary report on a series of patients with diminished symptomatic complications of osteoporosis. Mayo Clin Proc 68: 1171–1176

    Article  CAS  Google Scholar 

  3. Kaplan RS et al. (1996) Effect of back supports on back strength in patients with osteoporosis: a pilot study. Mayo Clin Proc 71: 235–241

    Article  CAS  Google Scholar 

  4. Sinaki M et al. (1996) Can strong back extensors prevent vertebral fractures in women with osteoporosis? Mayo Clin Proc 71: 951–956

    Article  CAS  Google Scholar 

  5. Pfeifer M et al. (2004) Effects of a new spinal orthosis on posture, trunk strength, and quality of life in women with postmenopausal osteoporosis: a randomized trial. Am J Phys Med Rehabil 83: 177–186

    Article  Google Scholar 

  6. Lauritzen JB (1996) Hip fractures: incidence, risk factors, energy absorption, and prevention. Bone 18: 65S–75S

    Article  CAS  Google Scholar 

  7. Kannus P et al. (1999) Comparison of force attenuation properties of four different hip protectors under simulated falling conditions in the elderly: an in vitro biomechanical study. Bone 25: 229–235

    Article  CAS  Google Scholar 

  8. Parker MJ et al. (2006) Effectiveness of hip protectors for preventing hip fractures in elderly people: systematic review. BMJ 332: 571–574

    Article  Google Scholar 

  9. Fleurence RL (2004) Cost-effectiveness of fracture prevention treatments in the elderly. Int J Technol Assess Health Care 20: 184–191

    Article  Google Scholar 

  10. Singh S et al. (2004) Cost-effectiveness of hip protectors in the prevention of osteoporosis related hip fractures in elderly nursing home residents. J Rheumatol 31: 1607–1613

    PubMed  Google Scholar 

  11. Parkkari J et al. (1998) Acceptability and compliance with wearing energy-shunting hip protectors: a 6-month prospective follow-up in a Finnish nursing home. Age Ageing 27: 225–229

    Article  CAS  Google Scholar 

  12. van Schoor NM et al. (2002) Acceptance and compliance with external hip protectors: a systematic review of the literature. Osteoporos Int 13: 917–924

    Article  CAS  Google Scholar 

  13. Kannus P and Parkkari J (2006) Prevention of hip fracture with hip protectors. Age Ageing 35: ii51–ii54

    Article  Google Scholar 

  14. Patel S et al. (2003) Acceptability and compliance with hip protectors in community-dwelling women at high risk of hip fracture. Rheumatology (Oxford) 42: 769–772

    Article  CAS  Google Scholar 

  15. Cameron ID and Quine S (1994) External hip protectors: likely non-compliance among high risk elderly people living in the community. Arch Gerontol Geriatr 19: 273–281

    Article  CAS  Google Scholar 

  16. Villareal DT et al. (2003) Effects of exercise training added to ongoing hormone replacement therapy on bone mineral density in frail elderly women. J Am Geriatr 51: 985–990

    Article  Google Scholar 

  17. Sinaki M et al. (2005) Significant reduction in risk of falls and back pain in osteoporotic-kyphotic women through a Spinal Proprioceptive Extension Exercise Dynamic (SPEED) program. Mayo Clin Proc 80: 849–855

    Article  Google Scholar 

  18. Miyakoshi N et al. (2005) Factors related to spinal mobility in patients with postmenopausal osteoporosis. Osteoporos Int 16: 1871–1874

    Article  Google Scholar 

  19. Rubin C et al. (2006) Low-level mechanical signals and their potential as a non-pharmacological intervention for osteoporosis. Age Ageing 35: ii32–ii36

    Article  Google Scholar 

  20. Rubin C et al. (2004) Prevention of postmenopausal bone loss by a low-magnitude, high-frequency mechanical stimuli: a clinical trial assessing compliance, efficacy, and safety. J Bone Miner Res 19: 343–351

    Article  Google Scholar 

  21. Holick MF (2005) The vitamin D epidemic and its health consequences. J Nutr 135: 2739S–2748S

    Article  CAS  Google Scholar 

  22. Holick MF (2006) High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc 81: 353–373

    Article  CAS  Google Scholar 

  23. Holick MF (2004) Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 80: 1678S–1688S

    Article  CAS  Google Scholar 

  24. Holick MF (2005) Vitamin D for health and in chronic kidney disease. Semin Dial 18: 266–275

    Article  Google Scholar 

  25. Tinetti ME et al. (2006) Fall-risk evaluation and management: challenges in adopting geriatric care practices. Gerontologist 46: 717–725

    Article  Google Scholar 

  26. Rubenstein LZ et al. (1996) Falls and fall prevention in the nursing home. Clin Geriatr Med 12: 881–902

    Article  CAS  Google Scholar 

  27. Krauss MJ et al. (2005) A case-control study of patient, medication, and care-related risk factors for inpatient falls. J Gen Intern Med 20: 116–122

    Article  Google Scholar 

  28. Ganz DA et al. (2007) Will my patient fall? JAMA 297: 77–86

    Article  Google Scholar 

  29. Vu MQ et al. (2004) Falls in the nursing home: are they preventable? J Am Med Dir Assoc 5: 401–406

    Article  Google Scholar 

  30. Wolf SL et al. (1996) Reducing frailty and falls in older persons: an investigation of tai chi and computerized balance training. Atlanta FICSIT Group. Frailty and Injuries: Cooperative Studies of Intervention Techniques. J Am Geriatr Soc 44: 489–497

    Article  CAS  Google Scholar 

  31. Greenspan AI et al. (2007) Tai chi and perceived health status in older adults who are transitionally frail: a randomized controlled trial. Phys Ther 87: 525–535

    Article  Google Scholar 

  32. Lim MR et al. (2007) Evaluation of the elderly patient with an abnormal gait. J Am Acad Orthop Surg 15: 107–117

    Article  Google Scholar 

  33. Garfin SR et al. (2006) Balloon kyphoplasty for symptomatic vertebral body compression fractures results in rapid, significant, and sustained improvements in back pain, function, and quality of life for elderly patients. Spine 31: 2213–2220

    Article  Google Scholar 

  34. Lavelle WF and Cheney R (2006) Recurrent fracture after vertebral kyphoplasty. Spine J 6: 488–493

    Article  Google Scholar 

  35. Rohlmann A et al. (2006) Spinal loads after osteoporotic vertebral fractures treated by vertebroplasty or kyphoplasty. Eur Spine J 15: 1255–1264

    Article  Google Scholar 

Download references

Acknowledgements

Désirée Lie, University of California, Irvine, CA, is the author of and is solely responsible for the content of the learning objectives, questions and answers of the Medscape-accredited continuing medical education activity associated with this article.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Julie T Lin.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lin, J., Lane, J. Nonpharmacologic management of osteoporosis to minimize fracture risk. Nat Rev Rheumatol 4, 20–25 (2008). https://doi.org/10.1038/ncprheum0702

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncprheum0702

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing