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  • Review Article
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Screening for frailty among seniors in clinical practice

Abstract

The normal course of aging is associated with gradual declines in a number of functional abilities. Patients who are at high risk of functional decline are described as frail or vulnerable. A screening tool to identify such patients is needed, as it has been shown that intervention can delay the onset and/or slow the progression of functional decline. This Review describes the methods currently available for nonspecialist evaluation of aging individuals, including behavioral, interview and questionnaire assessments. Such assessments can be undertaken during routine physician visits. In recognition of the time pressures on physicians, this article focuses on those measurements that are fairly comprehensive yet concise, easy to administer in an office setting, and available in English.

Key Points

  • Functional decline is a common accompaniment to old age, but is increasingly neither inevitable nor unmanageable

  • Screening for frailty among seniors should become a regular part of clinical encounters

  • A variety of methods of screening are available to physicians; specifically behavioral, interview and questionnaire assessments

  • These screening methods should be used in combination to screen for frailty

  • Large studies using combinations of screening methods are needed to develop an effective and efficient, but brief, protocol to screen for physical vulnerability

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References

  1. Folstein M et al. (1975) “Mini-Mental State”, a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189–198

    CAS  PubMed  Google Scholar 

  2. Beck AT et al. (1997) Screening for major depression disorders in medical inpatients with the Beck Depression Inventory for primary care. Behav Res Ther 35: 785–791

    CAS  PubMed  Google Scholar 

  3. Beck AT et al. (1997) Use of the Beck Anxiety and Depression Inventories for primary care with medical outpatients. Assessment 4: 211–219

    CAS  PubMed  Google Scholar 

  4. Liang MH (1990) The measurement paradox of disability and its implication for gerontology. In Challenges in Aging: the 1990 Sandoz Lectures in Gerontology, 223–231 (Eds Bergener M et al.) New York: Academic Press

    Google Scholar 

  5. Guralnik JM et al. (2000) Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. J Gerontol A Biol Sci Med Sci 55 (Pt A): M221–M231

    CAS  PubMed  Google Scholar 

  6. Mitnitski A et al. (2005) Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J Am Geriatr Soc 53: 2184–2189

    PubMed  Google Scholar 

  7. Fried LP et al. (2001) Frailty in older adults: evidence for a phenotype. Cardiovascular Health Study Collaborative Research Group. J Gerontol A Biol Sci Med 56 (Pt A): M146–M156

    CAS  Google Scholar 

  8. Rockwood K et al. (2005) A global clinical measure of fitness and frailty in elderly people. Can Med Assoc J 173: 489–495

    Google Scholar 

  9. Rockwood K (2005) What would make a definition of frailty successful? Age Ageing 34: 432–434

    PubMed  Google Scholar 

  10. Hammerman D (1999) Toward an understanding of frailty. Ann Intern Med 130: 945–950

    Google Scholar 

  11. Saliba D et al. (2001) The Vulnerable Elders Survey: a tool for identifying vulnerable older people in the community. J Am Geriatr Soc 49: 1691–1699

    CAS  PubMed  Google Scholar 

  12. Ferrucci L et al. (2004) Interventions on Frailty Working Group. Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail older persons: a consensus report. J Am Geriatr Soc 52: 625–634

    PubMed  Google Scholar 

  13. Gill T and Kurland B (2003) The burden and patterns of disability in activities of daily living among community-living older persons. J Gerontol A Biol Sci Med Sci 58 (Pt A): 70–75

    PubMed  Google Scholar 

  14. Chang JT et al. (2004) Interventions for the prevention of falls in older adults: a meta-analysis of randomised clinical trials. BMJ 328: 680–686

    PubMed  PubMed Central  Google Scholar 

  15. Sloss EM et al. (2000) Selecting target conditions for quality of care improvement in vulnerable older adults. J Am Geriatr Soc 48: 363–369

    CAS  PubMed  Google Scholar 

  16. Boult C et al. (1994) A controlled trial of outpatient geriatric evaluation and management. J Am Geriatr Soc 42: 465–470

    CAS  PubMed  Google Scholar 

  17. Reuben D et al. (2003) Restructuring primary care practices to manage geriatric syndromes: the ACOVE-2 intervention. J Am Geriatr Soc 51: 1787–1793

    PubMed  Google Scholar 

  18. Higashi T et al. (2005) Quality of care is associated with survival in vulnerable older patients. Ann Intern Med 143: 274–281

    PubMed  Google Scholar 

  19. Teno J et al. (1990) Multiple stumbles: a risk factor for falls in community-dwelling elderly. J Am Geriatr Soc 38: 1321–1325

    CAS  PubMed  Google Scholar 

  20. Morley J (2003) Mobility performance: a high-tech test for geriatricians. J Gerontol A Biol Sci Med Sci 58 (Pt A): 712–714

    PubMed  Google Scholar 

  21. Mathias A et al. (1986) Balance in elderly patients: the “get-up and go” test. Arch Phys Med Rehabil 67: 387–394

    CAS  PubMed  Google Scholar 

  22. Saliba D et al. (2000) Identifying a short functional disability screen for older persons. J Gerontol A Biol Sci Med Sci 55 (Pt A): M750–M756

    CAS  PubMed  Google Scholar 

  23. Nourhashemi F et al. (2001) Instrumental activities of daily living as a potential marker of frailty: a study of 7,364 community-dwelling elderly women (the EPIDOS Study). J Gerontol A Biol Sci Med Sci 56 (Pt A): M448–M453

    CAS  PubMed  Google Scholar 

  24. RAND Corporation (2001) Assessing care of vulnerable elders: a RAND Health project. Vulnerable elders survey (VES-13) [http://www.rand.org/health/projects/acove/ve_survey.html] (accessed 20 July 2006)

  25. Brody KK and Perrin NA (2002) The Frailty Wheel study: evaluation of a population-based screening technique modified for patient care settings. The Gerontological Society of America. Poster session: 24 November 2002

  26. Gill T et al. (2002) Underestimation of disability in community-living older persons. J Am Geriatr Soc 50: 1492–1497

    PubMed  Google Scholar 

  27. van Iersel MB and Rikkert MG (2006) Frailty criteria give heterogenous results when applied in clinical practice. J Am Geriatr Soc 54: 728–729

    PubMed  Google Scholar 

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Acknowledgements

The authors thank Dr Matthew Liang of Brigham and Women's Hospital and Harvard Medical School, for his advice and contribution throughout the project. The work was supported by the Boulos Hanna Summer Studentship at the Royal College of Surgeons in Ireland (RCSI) and by the Healthy Aging Research Programme (a cross-institutional project funded by the Health Research Board, which also involves Trinity College Dublin, the Queen's University of Belfast and the Economic and Social Research Institute, Dublin).

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Correspondence to Kristin M Corapi.

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The authors declare no competing financial interests.

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Corapi, K., McGee, H. & Barker, M. Screening for frailty among seniors in clinical practice. Nat Rev Rheumatol 2, 476–480 (2006). https://doi.org/10.1038/ncprheum0288

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