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Neural stem cell quiescence comes to an un-sticky end

Nature Cell Biology volume 16, pages 625627 (2014) | Download Citation

Cell–cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.

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Author information

Affiliations

  1. Katherine R. Long and Charles ffrench-Constant are at the MRC Centre for Regenerative Medicine, SCRM Building, Edinburgh bioQuarter, 5 Little France Drive, Edinburgh, EH16 4UU, UK

    • Katherine R. Long
    •  & Charles ffrench-Constant

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Competing interests

The authors declare no competing financial interests.

Corresponding authors

Correspondence to Katherine R. Long or Charles ffrench-Constant.

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DOI

https://doi.org/10.1038/ncb3003

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