Cadherins articles from across Nature Portfolio

Cadherins are transmembrane proteins that contain calcium-binding domains, termed 'cadherin repeats' in their extracellular regions. As the major constituents of adherens junctions, cadherins of adjacent cells mediate intercellular adhesion by interacting with each other, and by associating with specialized protein complexes linked to the actin cytoskeleton through their intracellular regions.

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