The mitochondrial network fragments during mitosis to allow proper segregation of the organelles between daughter cells. Two mitotic kinases, the cyclin B–CDK1 complex and Aurora A, are now shown to cooperate with the small G protein RALA and its effector RALBP1 to promote DRP1 phosphorylation and mitochondrial fission.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Activation of efficient DNA repair mechanisms after photon and proton irradiation of human chondrosarcoma cells
Scientific Reports Open Access 16 December 2021
-
Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes
Scientific Reports Open Access 25 January 2021
-
Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness
Oncogene Open Access 03 May 2018
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Westermann, B. Nat. Rev. Mol. Cell Biol. 11, 872–884 (2010).
Ishihara, N. et al. Nat. Cell Biol. 11, 958–966 (2009).
Wakabayashi, J. et al. J. Cell Biol. 186, 805–816 (2009).
Chen, H., McCaffery, J. M. & Chan, D. C. Cell 130, 548–562 (2007).
Ingerman, E. et al. J. Cell Biol. 170, 1021–1027 (2005).
Labrousee, A. M., Zappaterra, M. D., Rube, D. A. & van der Bliek, A. M. Mol. Cell 4, 815–826 (1999).
Smirnova, E., Griparic, L., Shurland, D. L. & van der Bliek, A. M. Mol. Biol. Cell.
Taguchi, N. et al. J. Biol. Chem. 282, 11521–11529 (2007).
Kashatus, D. F. et al. Nat. Cell Biol. 13, 1108–1115 (2011).
Ma, H. T. & Poon, R. Y. Biochem. J. 435, 17–31 (2011).
Feig, L. A. Trends Cell Biol. 13, 419–425 (2003).
Lim, K. H. et al. Mol. Cell. Biol. 30, 508–523 (2010).
Chang, C. R. & Blackstone, C. J. Biol. Chem. 282, 21583–21587 (2007).
Gomes, L. C., Di Benedetto, G. & Scorrano, L. Nat. Cell Biol. 13, 589–598 (2011).
Rambold, A. S., Kostelecky, B., Elia, N. & Lippincott-Schwartz, J. Proc. Natl Acad. Sci. USA 108, 10190–10195 (2011).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Yamano, K., Youle, R. Coupling mitochondrial and cell division. Nat Cell Biol 13, 1026–1027 (2011). https://doi.org/10.1038/ncb2334
Published:
Issue Date:
DOI: https://doi.org/10.1038/ncb2334
This article is cited by
-
Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes
Scientific Reports (2021)
-
Activation of efficient DNA repair mechanisms after photon and proton irradiation of human chondrosarcoma cells
Scientific Reports (2021)
-
Mitochondrial network remodeling: an important feature of myogenesis and skeletal muscle regeneration
Cellular and Molecular Life Sciences (2021)
-
Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness
Oncogene (2018)
-
The Parkinson’s gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes
Oncogene (2015)
