Aurora A, an integral mitotic kinase, is essential for microtubule dynamics of post-mitotic neurons. PKCζ activates Aurora A, which in turn phosphorylates NDEL1 to promote neurite extension. This raises the possibility that Aurora A may also be involved in establishing cell polarity and axon/dendrite elaboration in young neurons.
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Lefkowitz, G., Gleeson, J. Aurora A moonlights in neurite extension. Nat Cell Biol 11, 1053–1054 (2009). https://doi.org/10.1038/ncb0909-1053
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DOI: https://doi.org/10.1038/ncb0909-1053
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