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Motor-cargo release: CaMKII as a traffic cop

Nature Cell Biology volume 10, pages 35 (2008) | Download Citation

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The spatial and temporal regulation of motor-based transport is essential to ensure precise cargo delivery in all cell types. New light has been shed on mechanisms controlling cargo–motor interactions, with the finding that NMDA-cargo is released from KIF17 kinesin following motor phosphorylation by CaMKII near the synapse.

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Affiliations

  1. Shabeen Ally, Amber L. Jolly and Vladimir I. Gelfand are at the Department of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611.  vgelfand@northwestern.edu

    • Shabeen Ally
    • , Amber L. Jolly
    •  & Vladimir I. Gelfand

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DOI

https://doi.org/10.1038/ncb0108-3

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