The biotech sector's record in originating high-priority medicines exceeds that of the pharmaceutical industry, its costs are lower and its products have comparable revenues.
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References
- 1
US Food and Drug Administration. Manual of Policies and Procedures. Review Designation Policy; Priority and Standard http://www.fda.gov/downloads/AboutFDA/CentersOffices/ OfficeofMedicalProductsandTobacco/CDER/ManualofPoliciesProcedures/ucm082000.pdf (FDA, Washington, DC, 2013).
- 2
US Congressional Budget Office. Research and Development within the Pharmaceutical Industry http://www.cbo.gov/sites/default/files/cbofiles/ftpdocs/76xx/doc7615/10–02-drugr-d.pdf (CBO, Washington, DC, 2006).
- 3
US Food and Drug Administration. Guidance for Industry, Expedited Programs for Serious Conditions– Drugs and Biologics http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM358301.pdf (FDA, Washington, DC, 2014).
- 4
Trusheim, M. Aitken, M.L. & Berndt, E.R. Characterizing Markets for Biopharmaceutical Innovations: Do Biologics Differ from Small Molecules? NBER Working Papers 01/2010 (National Bureau of Economic Research, Washington, DC, 2010).
- 5
Ernst & Young. Beyond Borders: Matter of Evidence http://www.ey.com/Publication/vwLUAssets/Beyond_borders/$FILE/Beyond_borders.pdf (E&Y, London, 2013).
- 6
Kneller, R. Nat. Rev. Drug Discov. 9, 867–882 (2010).
- 7
Munos, B. Nat. Rev. Drug Discov. 8, 959–968 (2009).
- 8
Ernst & Young. Beyond Borders. Global Biotechnology Industry Report (E&Y, London, 2013).
- 9
Editors. Top 500 prescription drugs. PharmaLive, 5–14 (UBM Canon, Los Angeles, California, 2005).
- 10
Editors. Top 500 prescription medicines. PharmaLive, 5–17 (UBM Canon, Los Angeles, California, 2006).
- 11
Editors. Top 500 prescription medicines. PharmaLive, 5–16 (UBM Canon, Los Angeles, California, 2007).
- 12
Editors. Top 500 prescription medicines. PharmaLive, 5–27 (UBM Canon, Los Angeles, California, 2008).
- 13
Editors. Top 500 prescription medicines. PharmaLive, 5–40 (UBM Canon, Los Angeles, California, 2010).
- 14
Editors. Top 500 prescription medicines. PharmaLive, 6–40 (UBM Canon, Los Angeles, California, 2011).
- 15
Sellers, L.J. Top 50 Pharmaceutical Companies of 1999. Pharmaceutical Executive Magazine, 63–76 (Advanstar Communications, New York, NY, 2000).
- 16
Brichacek, A. Top 50 Pharmaceutical Companies of 2000. Pharmaceutical Executive Magazine (Advanstar Communications, New York, NY, 2001), 63–82.
- 17
Sellers, L.J., Feighan, C. & Kelley, G. Top 50 Pharmaceutical Companies of 2001. Pharmaceutical Executive Magazine, 61–80 (Advanstar Communications, New York, NY, 2002).
- 18
Sellers, L.J. Fourth Annual Pharm Exec 50. Pharmaceutical Executive Magazine, 43–52 (Advanstar Communications, New York, NY, 2003).
- 19
Sellers, L.J. Pharm Exec 50. Pharmaceutical Executive Magazine, 61–70 (Advanstar Communications, New York, NY, 2004).
- 20
Pharm Exec Staff. Pharm Exec 50. Pharmaceutical Executive Magazine, 85–95 (Advanstar Communications, New York, NY, 2005).
- 21
Pharm Exec Staff. Our 7th annual report on the world's top 50 pharmaceutical companies. Pharmaceutical Executive Magazine, 80–88 (Advanstar Communications, New York, NY, 2006).
- 22
Pharm Exec Staff. Pharm Exec 50. Pharmaceutical Executive Magazine, 100–110 (Advanstar Communications, New York, NY, 2007).
- 23
Pharm Exec Staff. Pharm Exec Top 50. Pharmaceutical Executive Magazine, 75–84 (Advanstar Communications, New York, NY, 2008).
- 24
Pharm Exec Staff. The Pharm Exec 50. Pharmaceutical Executive Magazine, 69–78 (Advanstar Communications, New York, NY, 2009).
- 25
Clinton, P. and Mozeson, M. Pharm Exec 50. Pharmaceutical Executive Magazine, 70–80 (Advanstar Communications, New York, NY, 2010).
- 26
Cacciotti, J. and Clinton, P. Pharm Exec 50. Pharmaceutical Executive Magazine, 42–56 (Advanstar Communications, New York, NY, 2011).
- 27
Clinton, P. and Cacciotti, J. Pharm Exec 50. Pharmaceutical Executive Magazine, 26–32 (Advanstar Communications, New York, NY, 2012).
- 28
Noor, W. and Kleinrock, M. Pharm Exec 50. Pharmaceutical Executive Magazine, 20–29 (Advanstar Communications, New York, NY, 2013).
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The author has financial interests in numerous biotechnology companies.
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Drakeman, D. Benchmarking biotech and pharmaceutical product development. Nat Biotechnol 32, 621–625 (2014). https://doi.org/10.1038/nbt.2947
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