Papers from the literature selected by the Nature Biotechnology editors (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Offspring from oocytes derived from in vitro primordial germ cell–like cells in mice

Hayashi, K. et al. Science doi:10.1126/science.1226889 (4 October 2012)

A physically transient form of silicon electronics

Hwang, S.-W. et al. Science 337, 1640–1644 (2012)

Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

Guo Lian, C. et al. Cell 150, 1135–1146 (2012)

Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes

Shim, S.-H. et al. Proc. Nat. Acad. Sci. 109, 13978–13983 (2012)

Complete Plasmodium falciparum liver-stage development in liver-chimeric mice

Vaughan, A.M et al. J. Clin. Invest. 122, 3618–3628 (2012)