The binding of T-cell receptors to peptide molecules not normally present in the body can trigger an immune response. Predicting which peptide a T-cell receptor will bind to — a difficult feat — has now been achieved. See Letters p.89 & p.94
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Reddy, S. The patterns of T-cell target recognition. Nature 547, 36–38 (2017). https://doi.org/10.1038/nature23091
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DOI: https://doi.org/10.1038/nature23091
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