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Molecular biology

A surprise beginning for RNA

Organic molecules called coenzymes are central to metabolism, but have also been found to act as components of RNA in bacteria. A study reveals how coenzymes are incorporated into RNA. See Letter p.444

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Figure 1: Capping mechanisms.

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References

  1. 1

    Topisirovic, I., Svitkin, Y. V., Sonenberg, N. & Shatkin, A. J. Wiley Interdisciplin. Rev. RNA 2, 277–298 (2011).

    CAS  Article  Google Scholar 

  2. 2

    Cahová, H., Winz, M.-L., Höfer, K., Nübel, G. & Jäschke, A. Nature 519, 374–377 (2015).

    Article  ADS  Google Scholar 

  3. 3

    Kowtoniuk, W. E., Shen, Y., Heemstra, J. M., Agarwal, I. & Liu, D. R. Proc. Natl Acad. Sci. USA 106, 7768–7773 (2009).

    CAS  Article  ADS  Google Scholar 

  4. 4

    Bird, J. G. et al. Nature 535, 444–447 (2016).

    CAS  Article  ADS  Google Scholar 

  5. 5

    Machnicka, M. A. et al. Nucleic Acids Res. 41, D262–D267 (2013).

    CAS  Article  Google Scholar 

  6. 6

    Martinez-Rucobo, F. W. et al. Mol. Cell 58, 1079–1089 (2015).

    CAS  Article  Google Scholar 

  7. 7

    Chen, Y. G., Kowtoniuk, W. E., Agarwal, I., Shen, Y. & Liu, D. R. Nature Chem. Biol. 5, 879–881 (2009).

    CAS  Article  Google Scholar 

  8. 8

    Jäschke, A., Höfer, K., Nübel, G. & Frindert, J. Curr. Opin. Microbiol. 30, 44–49 (2016).

    Article  Google Scholar 

Download references

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Correspondence to Andres Jäschke.

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Höfer, K., Jäschke, A. A surprise beginning for RNA. Nature 535, 359–360 (2016). https://doi.org/10.1038/nature18908

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