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Cell biology

Killer enzymes tethered

Caspase enzymes promote cell death, but are also involved in sperm development in fruit flies. The discovery that, in sperm, caspase activation is restricted to the surface of organelles called mitochondria sheds light on this unusual role.

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Figure 1: Caspase-mediated sperm development.

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Correspondence to Shigekazu Nagata.

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Nagata, S. Killer enzymes tethered. Nature 533, 475–476 (2016). https://doi.org/10.1038/nature18439

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