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Cell biology

Killer enzymes tethered

Nature volume 533, pages 474476 (26 May 2016) | Download Citation

Caspase enzymes promote cell death, but are also involved in sperm development in fruit flies. The discovery that, in sperm, caspase activation is restricted to the surface of organelles called mitochondria sheds light on this unusual role.

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Author information

Affiliations

  1. Shigekazu Nagata is in the Laboratory of Biochemistry and Immunology, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

    • Shigekazu Nagata

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Correspondence to Shigekazu Nagata.

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DOI

https://doi.org/10.1038/nature18439

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