The detection of a single molecule anchored to circulating extracellular vesicles allows late-stage pancreatic cancer to be identified from just one drop of a patient's blood. See Article p.177
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Candidate biomarkers of EV-microRNA in detecting REM sleep behavior disorder and Parkinson’s disease
npj Parkinson's Disease Open Access 10 January 2024
-
Differential proteomic analysis of plasma-derived exosomes as diagnostic biomarkers for chronic HBV-related liver disease
Scientific Reports Open Access 24 August 2022
-
The molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectives
Signal Transduction and Targeted Therapy Open Access 05 July 2021
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Notes
References
Melo, S. A. et al. Nature 523, 177–182 (2015).
Kleeff, J. et al. J. Clin. Invest. 102, 1662–1673 (1998).
Aikawa, T. et al. J. Clin. Invest. 118, 89–99 (2008).
Whipple, C. A., Young, A. L. & Korc, M. Oncogene 31, 2535–2544 (2012).
Kim, J. W. et al. Clin. Cancer Res. 11, 1010–1020 (2005).
Zhou, H. et al. Kidney Int. 70, 1847–1857 (2006).
Skog, J. et al. Nature Cell Biol. 10, 1470–1476 (2008).
Peinado, H. et al. Nature Med. 18, 883–891 (2012).
Logozzi, M. et al. PLoS ONE 4, e5219 (2009).
Jakobsen, K. R. et al. J. Extracell. Vesicles 4, 26659 (2015).
Madhavan, B. et al. Int. J. Cancer 136, 2616–2627 (2015).
Trams, E. G., Lauter, C. J., Salem, N. Jr & Heine, U. Biochim. Biophys. Acta 645, 63–70 (1981).
Johnstone, R. M., Adam, M., Hammond, J. R., Orr, L. & Turbide, C. J. Biol. Chem. 262, 9412–9420 (1987).
Gould, S. J. & Raposo, G. J. Extracell. Vesicles 2, 20389 (2013).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Théry, C. Diagnosis by extracellular vesicles. Nature 523, 161–162 (2015). https://doi.org/10.1038/nature14626
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature14626
This article is cited by
-
Candidate biomarkers of EV-microRNA in detecting REM sleep behavior disorder and Parkinson’s disease
npj Parkinson's Disease (2024)
-
Synthetic miR-26a mimics delivered by tumor exosomes repress hepatocellular carcinoma through downregulating lymphoid enhancer factor 1
Hepatology International (2023)
-
Roles of extracellular vesicles on macrophages in inflammatory bone diseases
Molecular and Cellular Biochemistry (2023)
-
The Detection of Urinary Exosomal miRNAs for Cancer Diagnostics and Prognostics
BioChip Journal (2023)
-
Differential proteomic analysis of plasma-derived exosomes as diagnostic biomarkers for chronic HBV-related liver disease
Scientific Reports (2022)