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Metabolism

Growth in the fat lane

Analysis of endothelial cells, which are involved in blood-vessel formation, unexpectedly reveals that proliferation in this cell type depends on fatty-acid oxidation to support DNA synthesis. See Article p.192

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Figure 1: Metabolic pathways in blood-vessel formation.

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Correspondence to Ralph J. DeBerardinis.

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Egnatchik, R., DeBerardinis, R. Growth in the fat lane. Nature 520, 165–166 (2015). https://doi.org/10.1038/nature14375

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