The finding that absence of the enzyme CTPS1 underlies a form of human immunodeficiency highlights the role of metabolism in immune responses and suggests avenues for treating diseases such as leukaemia. See Letter p.288
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Veillette, A., Davidson, D. When lymphocytes run out of steam. Nature 510, 222–223 (2014). https://doi.org/10.1038/nature13346
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DOI: https://doi.org/10.1038/nature13346